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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afa0bbe4c6f0dd131d61c6d19526a14bf24159d22f822305771635349d68cf2c' 
  AND token = '7SgWIe42UY7U6vdyktbZuN7/apt4fKP3WchXN1bQDVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}