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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '000ea927efe403c13eb1e4eb6b6fbe21d6eb083d44ca9d781230e91881660022' 
  AND token = 'aIU3na1uV1uPQSt7eHkC/iZPau+E3DybLpLL/YWcJtc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}