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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1899f18552163a83ecf55997c50296738bb5abefca7508e717a6bce8065a1c7' 
  AND token = 'icw/rmHDWV23mwTMr6j2LR3RoELSOnNVTPkGBK/01r8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}