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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3190f729b6e8bf4540abbddcfe9bb94df095c8129eeb77de6f92e804998fbad0' 
  AND token = 'gRuSyhtFdo8G/TJbUUHFjaXNSGCjC5tuHYDWhGTJ+x4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}