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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e58b3b49be9e010e82479cf1726bfb5720fc59d2bd7d63541b0edfb8780e8c6' 
  AND token = 'S3jU0U87pg/Whys5E8HvXAvysaiN97FFeES20SAw4OY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}