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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12f45dfe30e9e54676b8c49a512620bab8d770db045a3861c2bb8338a4e1439d' 
  AND token = 'Y0ER+z29j9iyx5qTn5/YN92ULEshgmPNTBCb3k8995k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}