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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de6818e006baff497afce8fb21908e043ea4645853f752e8f25615748eefe41f' 
  AND token = 'eYhKq/28Z4TzB72DewKdlKxjQMGpr/rUa5lDgbp6eLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}