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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5371395e12337830bcaba37eab7c7eb22ce6f328652e6bda0ae8491e9cf9e149' 
  AND token = 'DYcrirt0m4uJof+WGoj1YCgRxhOaYS6vp0DNouPJANk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}