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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80bcc5b6c5a86424f6d477e58d0d048d8cba5f87b0f88c1d8e3075bf41557d00' 
  AND token = '7WzaZeEwzzmGBICRM75baGuOYJVzTnsu717CMdLAC0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}