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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0296e15007487a3a1e7008f54e100ad9ee5db30f5d3dbc8d00b872d46406afa' 
  AND token = 'oyZVnArlyhaLWOOUQ/bn6fJ7ENpNBkBAi4rCQ2LcrM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}