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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f52263481d3df44b55a5244dbc846ed5d6275916827db575147839194c2fffad' 
  AND token = '9sG5jSPyS244mqmrjCVbr4l+nnPdZuvA3r8I6q0psQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}