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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a4a353b38a42aec2cb8e5dc9b1aa16d790876b3e640b967da21f56c20a1a166' 
  AND token = '60eHSOkMhXi7FKjhEr2pV4PhXf0CaNhfV7aejOnDrVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}