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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d58188101eccbae2722cc0cdf83ca3c0e5aa26049678d1200ed7e2235f6f343' 
  AND token = 'Lg+GJepdV5xJrZ5VchnKxc2VbR1bzn5LDM+CBkcr078=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}