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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac7925acdf83245c80c84e321096602fbe66b7d6ec72aef7574cb864c4f64e8b' 
  AND token = 'uH6cOGp2KeYa666sbf4d1OxKf3Rer3cMUqfLSUMNSgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}