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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c321916037e783b49d272b3b32b5f4f10890177386554818c3aba949ee001371' 
  AND token = 'kLbWPiPg4dN+I5FviwiUsE+7+1Fwa6PWWn3Wxj1jdV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}