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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25cd6e465cf49d8f216b8877c1a740176d7fc57218e4345a0e184363f4162deb' 
  AND token = 'WHY3VGl1812MPHNXl6G7Mfp6q4lXbpIRp2bN67Nc+zE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}