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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6829206dcdf85553b47408a985f159019eead189f7c3fe27c713a22a2c53135' 
  AND token = 'V1qtceXjnYc6JQ+sFOflRn+osfKgmciG7D/3OtjP+5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}