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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5db1d9daec44f96c646643c043c2f9e332051d7fa05f1f96b2da8b33c083fe2e' 
  AND token = 'WbbhohYWECKDoXYBlIo+ukZTBUk0qxRhQM2PXxRKl/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}