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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4d439b2992b1435028cdcf9c3f801ba3a1f43aaffade0a6505b671a24081900' 
  AND token = '5jVTyEfGOtuH/4t1MjZnpaqHnaevPsCwgZKOBjam6Io=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}