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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '729462e5853c9c987d5a63907ab406d44b9a303ed6c817bc28b1120bb74c85f4' 
  AND token = 'DoAc991ePzHDjySdD/SDKH3su80oSM2cn04xnfLd9xM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}