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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5366edca252ab1d0b30f34f6225832fe7e1f4e7f79212c61b55c404f31fde1d1' 
  AND token = 'Kyyr5xK1bJ/mPslijg5di7U+oOQQ7lI2dQhlS8TGTCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}