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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05ff20e8776825e05a6ade12d49daff485deac1a4714a7c10f7b45389894108a' 
  AND token = 'qY8sP5QTFDyDcU8YD1eRbbcjFicFxqFwMuqBrP8pan0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}