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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c09877d49449a9d7025b7487ec3ec17513bc17ea2a51c80e9105fd473282da0' 
  AND token = 'eAPeHx+5w85nnDnorQgTE2LQ9iaEDxBwkmbMoTykRB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}