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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '558ed93439f6e6f25342df3f7a0251ee24b75c66e9911c49ee5ec2d2d5818502' 
  AND token = 'RrQqghPR2hocbSANQh0qjoeIyUPoXe7AL6S0Mkz/ch4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}