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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f27492729385a6029d140fce5bcc4afd7ebacd90d06c0f7191c1c5f2e6e7015b' 
  AND token = '3LLlCvSwjZZKOvrYywbi12ZwG9/3WXy4o7Gk6/CqYZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}