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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02e6abb1426599516e2a50d1a149b94114e10644fbc3b01d43fe495ca995a27c' 
  AND token = '9XHvFIlFiBXb8cZJywQ1Z46VbEgUhxoVDc7FKJGwNFA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}