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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0be1e48189e6b0b72f34600773a02def2cf81877c3ed3dc390f60ad41f6fd9f' 
  AND token = 'TuxE49zVD94reW85dpb0uCizN8FW1F2VRLhLpp509g0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}