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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d95ad7d7e0c9d062dfb6093792ded58832e2481b9f7828e84aeb6a8ba9ceb18' 
  AND token = 'C0xNN2ZDGK1m8vj/MoS+sUX/crq2UO87YFRmHRfg3y4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}