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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0526b81af74d58d7b0c23fda78cd37011a77b6a4129aeb0193b0c4db2ed6d6c' 
  AND token = 'FIJORTICpq9WAiU1SC6NdlE4gygCJ0E2UYss8Y3b49A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}