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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd244699ea06d94d1dbe6f7106be8eba467e0b2d6fd1529d5a76c04279822cf3c' 
  AND token = '17VCOC7OAuRo4kLbBSmBd1iDM24pfGWdGuzpu/Aw1g8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}