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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4772699c4fd3a42c170e1334d5563b989e57288feed7a58d278833fabe816685' 
  AND token = 'ZuS06oPI8bpJy/f7iqgJNdXEW3/9qNqi487CT4yUD5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}