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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '433ddaec75027ffb98f4c176d6763a776ea4d8aad27aa57081241fd483b3d89f' 
  AND token = 'qMv2EyYZhYfEfi8TXt27d17W9S5qb7/oES7qT2tK+QA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}