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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f0ea2f26b7bb007a5a2c88c52d91a8c18bdc2b59889979dd546cef206d56a2b' 
  AND token = '9lWC52Y2DwIVDO+LhZJuWlfUJtRoHk87XzfjY5i1S6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}