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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86295d1a691965776adbcf5cd131b0738ba1505bcf6a16f42b5e564b2082749b' 
  AND token = '+f1BY+A2d46f2AbDqzyVaT5uYcUCjJs12DCo57uXJ38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}