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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e67df40e9031d727c06e0142c57b32e47ddfb7593a13013b27870547a3401c46' 
  AND token = 'bQKE9Dy/ZCJSxbKsM8d7OfMW7/8YEE7p7fyJsFCk9F8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}