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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c41a022831f77c204c9dd5198f26a770dc04ee4f421ef26a5c781f47bd95da57' 
  AND token = 'TVwVUk26EATYnlWM/y+vnhJ+9KEyinHjyb/DVUJ2JQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}