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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '684b1d22bfef155d46989d6cca363ec45821a7d7ebdf8153c564fb09422032f1' 
  AND token = 'Yuk6sKsbq3I0ddmOSjrbLsEj1EczraYqi+r0uRjwyOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}