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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ff64d88503bb300930d6c5db34c019c834dbd8f9658df0e707b7157b32e2db0' 
  AND token = 'edOYuUObjQ/W/9iiU4NBZ5Dx8K+1c7PWbMxHQJNwVaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}