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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa866399b61ac17780d5163a956d44f4dc039ba71c10b52eccb6fe39c8457400' 
  AND token = 'PxJ9AOhAQspPb0vcBEACBKZD4CfyJVGY3OnlIo8mCOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}