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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24ba19fabf4a309cb2a3678a08e4476da7a1677715ba422421f19d775c36df66' 
  AND token = 'MPLu0vKrRJv1dpkFToKmDo2vcM5pQsvo8izMY8m/0o8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}