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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7596c41ddef1891bef7f6094f460f1491cdeebebaf70ba057f0f74e49b1ddd2f' 
  AND token = 'S7z3VwdYLrcerO65Rn/6JwoJlMNYmeaKW5T0xXg5rVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}