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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6c9808f0b44b4d59e989a5169b71bf26f0ecd615280c5d3784fcf3ebc27df31' 
  AND token = 'tO/ab6gWG8qwIu849G0O4sMiMEMiHqUEfWD5WR6hDps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}