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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '216516b03825e146fb80c9e2e4410facf493cac690e56f20ee1a8b0f9ffb0ca5' 
  AND token = '04a6ZmkDnqblNHajQqfc9nJzClhUB9P475ZLx9qhCJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}