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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6e2e0107e79263655cc9ae281ad1317766f6ad48a9aca957f21a2999436af22' 
  AND token = 'IauClPPaAKHPTh2kub82lji0SUdTeVtcnikQR/v+JUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}