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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '380e67da89a4e958c2a9cb9d061a25c8b74c5199c6bd6290490bc061be0f09b7' 
  AND token = '57u8y9s4dpyLkXFrBL16ueRx3SAgRxXRtAi5gWfqmNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}