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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9b07165750fe05663b6ddcecfe3cb6e541f0bdc0e3340bfa030d581b63e8bbb' 
  AND token = 'VniL2rjp+XoDJg3Tt2wROKC1eUTHjcNVf5c2l5NO6FQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}