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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca349f37af0087ae5c59c5924517253bd6eef26f7adb81097e5cab0d2507fdd0' 
  AND token = 'Flk1GYhH3AdwgbWvyfbq5O3Rc/omNFS9Vvw5i1WiBqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}