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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '051e6655cfa1a9919fbeda17fb37d607f1e003d009bd85db3787f49cbb4a4463' 
  AND token = '44SyU3nSisnexchpjkyM+sdCA89k2hjzAwfBIpxbuhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}