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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12e4d8e844aa8025c928db1bdcca45f59b09cfa6754efce9fc4b9f348859cd89' 
  AND token = 'ckejgWZEX1w8WkkmvRyuNNgFGTbRmGtKaR0MTLyqfAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}