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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53ad6a3f14d24871d073a08c5790f6d5619131fd0141297909d0a6f18ce4021d' 
  AND token = 'nHGTEO6VwPghpr1ycjbswm+Ox8as0P19ncECwH2pIxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}